What
is this medicine for?
FOSAMAX helps protect your bones from breaking. Osteoporosis makes bones
thinner and more fragile — increasing the risk of fractures, particularly of
the spine, hip, and wrist. FOSAMAX works by slowing down the natural process of
bone removal, which helps preserve bone density and significantly reduces
fracture risk.
It is used to lower fracture risk due to osteoporosis and also during
prostate cancer management to remedy the bone loss associated with androgen
deprivation therapy.
It is taken once a week — a single tablet every week on the same day.
|
🚨 CRITICAL INSTRUCTIONS
— MUST FOLLOW EXACTLY |
This medicine must be
taken in a very specific way to protect your food pipe (oesophagus) from
serious irritation and ulceration. Read the instructions below carefully. Not
following them can cause severe oesophageal damage. |
How
do I take it — step by step?
• Choose one day of the week (e.g.
every Monday) — take it on the same day every week
• Take it FIRST THING IN THE MORNING,
before any food, drink, or other medicines
• Take with a FULL GLASS of plain water
only (at least 200 mL) — NOT juice, tea, coffee, or mineral water
• Swallow the tablet whole — do NOT
crush, chew, or let it dissolve
• STAY UPRIGHT (sitting or standing)
for at least 30 minutes after taking the tablet — do not lie down
• Do not eat, drink (except plain
water), or take other medicines for at least 30 minutes after
• Take your calcium and Vitamin D
supplements at a different time of day — NOT at the same time as FOSAMAX
Why
are these instructions so important?
Alendronate tablets can irritate and ulcerate the oesophagus if they do
not pass quickly to the stomach. Staying upright and taking with a full glass
of water ensures the tablet moves rapidly through the oesophagus. If you
experience any pain on swallowing, new heartburn, or chest pain after taking
FOSAMAX, stop and contact your doctor.
What
side effects might I notice?
Gastrointestinal (most common):
• Heartburn, abdominal discomfort, or
nausea — usually related to not following administration instructions
• Difficulty swallowing — stop
immediately and contact your doctor
Bone and muscle:
• Bone, joint, or muscle pain — can
sometimes be severe; usually resolves after stopping
Rare but serious:
• Osteonecrosis of the jaw (ONJ) — rare
at standard doses; a section of jawbone may be exposed, particularly after
dental extractions. Tell your dentist you take this medicine.
• Atypical femoral fractures — rare
stress fractures of the thigh bone with very long-term use (5+ years); report
any new thigh or groin pain
Important
reminders
• Tell your dentist before ANY dental
procedures that you take FOSAMAX
• After 5 years of treatment, your
doctor will review whether to continue, take a break, or switch treatment
• Always take your calcium and Vitamin
D supplements — these support the medicine's effect on your bones
Frequently
Asked Questions
❓ Why must I stay upright for 30 minutes?
Alendronate tablets can irritate and ulcerate the oesophagus if they sit
there too long. Staying upright and taking a full glass of water ensures the
tablet passes rapidly to your stomach. Lying down allows the tablet to sit in
the oesophagus, potentially causing serious ulceration.
❓ Can I take FOSAMAX with my other morning medicines?
No — FOSAMAX must be taken first, with only plain water, before any other
medicines, food, or drink. Other medicines (including calcium, vitamins, and
antacids) must be taken at least 30 minutes later. They reduce FOSAMAX
absorption significantly if taken at the same time.
❓ How long do I need to take FOSAMAX?
Osteoporosis is a long-term condition. Most guidelines recommend
reviewing treatment after 5 years. At that point your doctor will assess
whether to continue, take a 'drug holiday', or switch treatment based on your
fracture risk and bone density. Never stop without discussing with your doctor
— stopping abruptly allows bone loss to resume.
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