Neurocare plus caps 30s

What Is NEUROCARE PLUS?

Neurocare Plus is a carefully designed combination capsule that brings together five scientifically validated ingredients, each targeting a different aspect of nerve health, nerve pain, and nerve repair.

Pregabalin is the prescription-strength nerve pain medicine that calms overactive, pain-signalling nerves by binding to calcium channels and reducing the release of excitatory neurotransmitters, providing meaningful relief from the burning, shooting, or electric-shock-like pain of neuropathy.

Alpha Lipoic Acid (ALA) is a powerful antioxidant, uniquely soluble in both fat and water, that neutralises the oxidative stress responsible for damaging nerve fibres, particularly in diabetes.

Methylcobalamin is the most active, neurotropic form of Vitamin B12 that directly supports myelin sheath repair, the protective coating around nerve fibres that, when damaged, leads to neuropathy.

Pyridoxine (Vitamin B6) supports neurotransmitter synthesis and nerve impulse conduction. Folic Acid is essential for neurological health, DNA repair in nerve cells, and reducing homocysteine levels; elevated homocysteine is associated with nerve and vascular damage.

What Is It Used For?

Neurocare Plus is prescribed for people living with neuropathic pain, the chronic, often debilitating pain that arises from damaged or dysfunctional nerves, typically felt as burning, shooting, stabbing, tingling, or electric-shock sensations, most commonly in the feet and hands.

Neurocare Plus primary use in Kenya is for diabetic peripheral neuropathy, one of the most common and distressing long-term complications of diabetes, where chronically elevated blood sugar progressively damages nerve fibres. By combining Pregabalin's pain-relieving action with the neuroprotective and nerve-regenerating properties of ALA and B vitamins, Neurocare Plus addresses both the symptoms and the underlying nerve damage simultaneously. It is also used for post-herpetic neuralgia (nerve pain after shingles), chemotherapy-induced peripheral neuropathy, alcoholic neuropathy, and neuropathy related to B-vitamin deficiencies.

For patients on long-term Metformin therapy, which is known to deplete Vitamin B12 over time, the Methylcobalamin and Folic Acid components provide critical nutritional nerve support alongside the Pregabalin pain control.

Starting Dose

Pregabalin is typically started at a low dose and increased gradually. Follow your doctor's specific titration schedule, do not increase the dose on your own.

Typical Dosing

Usually taken once or twice daily as directed by your doctor. The Pregabalin component determines the dosing frequency.

With or Without Food

Can be taken with or without food. If stomach discomfort occurs, take with food.

Morning Preferred

If once-daily dosing, morning is preferred, ALA can have a mild energising effect that may interfere with sleep if taken late in the day.

Do Not Stop Suddenly

Never stop Neurocare Plus abruptly, the Pregabalin component causes withdrawal symptoms if stopped suddenly. Always taper gradually under your doctor's guidance.

Missed Dose

Take as soon as you remember. If close to the next dose, skip the missed one. Never double dose.

Duration

Minimum 3 months for meaningful nerve repair benefit from the nutritional components. The Pregabalin component provides pain control throughout. Your doctor will determine the overall treatment duration.

Renal Adjustment

Pregabalin dose must be reduced in kidney disease, confirm eGFR before starting and periodically during treatment.

Common Side Effects

·       Dizziness (very common with Pregabalin, particularly when starting or increasing dose)

·       Drowsiness and fatigue

·       Dry mouth

·       Blurred vision

·       Swollen ankles or feet (peripheral oedema, Pregabalin)

·       Weight gain

·       Bright yellow urine (B vitamin excretion, completely harmless)

·       Mild nausea or stomach discomfort (take with food to reduce)

Uncommon Side Effects

·       Memory or concentration difficulties

·       Mood changes or euphoria (Pregabalin misuse potential, take only as prescribed)

·       Constipation

·       Mild blood glucose lowering (ALA, monitor if on insulin or sulphonylureas)

·       Skin rash (rare allergic reaction)

Serious Side Effects, Seek Immediate Medical Attention

·       Suicidal ideation or worsening depression, report any mood changes, thoughts of self-harm, or unusual behaviour to your doctor immediately

·       Severe allergic reactions including angioedema (swelling of face, lips, tongue, or throat, seek emergency care)

·       Respiratory depression, especially if combined with opioids, benzodiazepines, or alcohol (potentially life-threatening)

·       Pregabalin dependence and withdrawal; do not stop abruptly

·       Misuse and abuse potential; take only as prescribed

·       MISUSE AND DEPENDENCE: Pregabalin has significant misuse and dependence potential, particularly at higher doses. Neurocare Plus must be taken only as prescribed, do not increase the dose without medical advice and do not share with others.

·       DRIVING: Pregabalin causes dizziness, blurred vision, and drowsiness, do not drive or operate machinery until you know how Neurocare Plus affects you. This is especially important in the first few weeks or after any dose increase.

·       DO NOT STOP SUDDENLY: Abruptly stopping Pregabalin causes withdrawal symptoms, anxiety, insomnia, nausea, sweating, and in rare cases seizures. Always reduce the dose gradually under medical guidance.

·       OPIOID AND CNS DEPRESSANT COMBINATION: Combining Pregabalin with opioids (tramadol, morphine, codeine), benzodiazepines, or alcohol significantly increases the risk of life-threatening respiratory depression, avoid these combinations.

·       SUICIDAL THOUGHTS: A small number of patients on anticonvulsants experience changes in mood or thoughts of self-harm. Report any such changes to your doctor immediately.

·       BLOOD GLUCOSE: ALA has mild glucose-lowering properties, diabetic patients on insulin or sulphonylureas should monitor blood sugar when starting Neurocare Plus.

·       B6 ACCUMULATION: Do not take additional high-dose B6 supplements alongside Neurocare Plus; excess B6 over time can paradoxically cause nerve damage (pyridoxine neuropathy).

·       KIDNEY DISEASE: Pregabalin accumulates in renal impairment; check eGFR at baseline and periodically. Dose adjustment is mandatory.

·       ELDERLY: Higher risk of falls from dizziness and unsteadiness; use lowest effective dose and monitor closely.

Opioids (tramadol, morphine, codeine, oxycodone): Risk of life-threatening respiratory depression; avoid or use with extreme caution under close medical supervision.

Benzodiazepines / CNS depressants (diazepam, sedatives, antihistamines): Additive sedation and respiratory depression risk.

Alcohol: Dramatically worsens sedation and coordination, avoid completely.

Insulin / Sulphonylureas: ALA has mild glucose-lowering properties, increased hypoglycaemia risk; monitor blood glucose.

Antacids (aluminium/magnesium hydroxide): Reduce Pregabalin absorption; separate by at least 2 hours.

Levodopa alone (Parkinson's, not carbidopa-levodopa): High B6 may reduce levodopa efficacy.

Thiazolidinediones (pioglitazone): Combined oedema risk with Pregabalin; monitor for fluid retention.

Thyroid medications: High-dose ALA may affect thyroid hormone levels, monitor if on levothyroxine.

Metformin: Complementary, Methylcobalamin and Folic Acid address Metformin-induced B12/folate depletion.

·       Store below 25°C in a cool, dry place.

·       Protect from light and moisture.

·       Keep in original blister packaging.

·       Keep out of reach of children.

·       Do not use after the expiry date.

Neurocare Plus is a prescription-only medicine (POM) in Kenya. Pregabalin is a controlled/monitored substance with significant misuse potential; a valid prescription from a registered physician, neurologist, diabetologist, or pain specialist is required. Available at Pharmily with a valid prescription.

Neurocare Plus with Pregabalin is a significantly upgraded formulation from the previously catalogued Neurocare Plus (ALA + Methylcobalamin + Pyridoxine + Folic Acid only).

The addition of Pregabalin elevates this from a nutritional supplement to a prescription-only medicine; dispensing requires a valid prescription and Pregabalin-specific counselling.

Q1: What is Neurocare Plus used for?

A: Neurocare Plus is used to treat neuropathic pain, the burning, shooting, or tingling pain caused by nerve damage, most commonly from diabetes, shingles, or nutritional deficiencies. It combines Pregabalin (a nerve pain medicine) with nutrients that protect and repair damaged nerve fibres.

Q2: Why does Neurocare Plus contain both Pregabalin and nutritional supplements?

A: Pregabalin controls the pain signals from damaged nerves, providing symptom relief. Alpha Lipoic Acid protects nerves from oxidative damage. 

Q3: How quickly will Neurocare Plus relieve my nerve pain?

A: Pregabalin typically begins to reduce pain within 1–2 weeks of reaching the right dose. The nutritional components (ALA, Methylcobalamin, Folic Acid) support nerve repair, a slower process that shows meaningful benefit over 3–6 months of consistent use.

Q4: Why does Neurocare Plus make me dizzy and sleepy?

A: Dizziness and drowsiness are the most common side effects of Pregabalin, particularly in the first 1–2 weeks or after a dose increase. They usually improve as your body adjusts. Rise slowly from bed or a chair, and avoid driving until the side effects settle.

Q5: Can I stop taking Neurocare Plus if my pain improves?

A: Never stop suddenly. Stopping Pregabalin abruptly can cause withdrawal symptoms, anxiety, sweating, insomnia, and in rare cases seizures. Your doctor will guide you on tapering the dose slowly and safely.